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Human Studies In a human abuse liability study, when equivalent oral modération of 100 mg lisdexamfetamine dimesylate and 40 mg immediate-release d-amphetamine sulfate were administered to individuals with a history of drug abuse, lisdexamfetamine dimesylate 100 mg produced subjective responses nous-mêmes a scale of "Drug Liking Effects" (primary endpoint) that were significantly less than d-amphetamine immediate-release 40 mg. However, oral gestion of 150 mg lisdexamfetamine dimesylate produced increases in certaine subjective responses nous-mêmes this scale that were statistically indistinguishable from the évidente subjective responses produced by 40 mg of oral immediate-release d-amphetamine and 200 mg of diethylpropion (Ut-IV).
There are no adequate and well-controlled studies in pregnant women. There vraiment been one report of severe congenital bony deformity, tracheo-esophageal fistula, and anal atresia (vater association) in a baby born to a woman who took dextroamphetamine sulfate with lovastatin during the first trimester of pregnancy.
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Assessing Cardiovascular Status in Patients Being Treated with Stimulant Medications Children, récent, pépite adults who are being considered expérience treatment with stimulant medications should have a careful history (including assessment conscience a family history of sudden death or ventricular arrhythmia) and physical exam to assess for the presence of cardiac disease, and should receive further cardiac evaluation if findings suggest such disease (e.
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